Once osteoarthritis pain start it is hard to stop. The new autologous protein solution intraarticular injection is designed to produce a groundbreaking autologous therapy to treat pain and slow the progression of cartilage degradation and destruction in the knee. The N-STRIDE system is a cell concentration system designed to concentrate anti-inflammatory cytokines and anabolic growth factors to significantly decrease pain and promote cartilage health.

Autologous protein solution contains concentrated white blood cells, platelets and plasma proteins in a small volume of plasma. The output is approximately a 2-3 cc anti-inflammatory solution.

In an osteoarthritic knee an increase in inflammatory cytokines results in cartilage degeneration and knee pain. The inflammatory proteins IL-1 and TNFa attack the cartilage. These inflammatory proteins must be stopped simultaneously to decrease pain and slow cartilage degeneration. The autologous protein solution treatment output introduces high level of IL-1ra, sIL-1R, sTNF-RI and sTNF-RII that block the inflammatory cytokines IL-1 and TNFa which may slow cartilage degeneration. While balance is being restored to the knee.

The autologous protein solution processes the patient’s own blood in the doctor’s office to concentrate white blood cells, platelets and plasma protein into a small volume of plasma. The output is approximately 2-3 ccs of anti-inflammatory solution and will be injected directly into the knee join (or other osteoarthritic joints). The treatment does not require admission to the clinic and the procedure does not exceed one hour.

Pain relief can be expected after one to two weeks. It is recommended to minimize the body activity level for 14 days after the injection.

• Significantly reduces pain associated with knee osteoarthritis.
• Significantly improves function in the osteoarthritic joint
• Stimulates cartilage cell proliferation
• Blocks cartilage destruction
• Slows cartilage degradation
• Poin-of-care
• Single injection

Worldwide clinical trials report excellent results, with the method being increasingly applied to specialist centers - a 70% improvement in pain for two years after a dose of autologous protein solution.